消化器内科学教室 スタッフ紹介

北部医療センター 学内講師 Assistant Professor
尾松 達司 Tatsushi Omatsu, M.D., Ph.D.

出身地 京都府

略 歴

2001年 京都府立医科大学医学部 卒業
京都府立医科大学附属病院 研修医
2003年 朝日大学附属村上記念病院 消化器内科 助教
2006年 京都府立医科大学大学院医学研究科 入学
2010年 京都府立医科大学大学院医学研究科 修了(医学博士)
国立病院機構舞鶴医療センター 消化器内科 医員
2011年 康生会武田病院 消化器センター 医長
ウェスタンオンタリオ大学 博士研究員
2013年 ハーバード大学マサチューセッツ総合病院 博士研究員
2017年 朝日大学病院 消化器内科 准教授
2021年 京都府立医科大学附属北部医療センター 消化器内科 講師(学内)

専 門

  • 消化器病
  • 消化器内視鏡
  • 消化管炎症
  • 腸管免疫


  • 日本内科学会 認定医
  • 日本消化器病学会 専門医・指導医・支部評議員
  • 日本消化器内視鏡学会 専門医・指導医・支部評議員
  • 日本消化管学会 胃腸科専門医・指導医
  • 日本ヘリコバクター学会 ピロリ菌感染症認定医
  • 日本抗加齢医学会 専門医
  • 日本炎症性腸疾患学会
  • 日本消化器免疫学会

業 績(筆頭著者)

  1. Yousif AS, Ronsard L, Shah P, Omatsu T, Sangesland M, Bracamonte Moreno T, Lam EC, Vrbanac VD, Balazs AB, Reinecker HC, Lingwood D. The persistence of interleukin-6 is regulated by a blood buffer system derived from dendritic cells. Immunity. 2021 Feb 9;54(2):235-246.
  2. Yasuda T, Yagi N, Omatsu T, Hayashi S, Nakahata Y, Yasuda Y, Obora A, Kojima T, Naito Y, Itoh Y. Benefits of linked color imaging for recognition of early differentiated-type gastric cancer: in comparison with indigo carmine contrast method and blue laser imaging. Surg Endosc. 2021 Jun;35(6):2750-2758.
  3. Yasuda T, Hiroyasu T, Hiwa S, Okada Y, Hayashi S, Nakahata Y, Yasuda Y, Omatsu T, Obora A, Kojima T, Ichikawa H, Yagi N. Potential of Automatic Diagnosis System with Linked Color Imaging for Diagnosis of Helicobacter Pylori Infection. Dig Endosc. 2020 Mar;32(3):373-381.
  4. Park SM, Omatsu T*, Zhao Y, Yoshida N, Shah P, Zagani R, Reinecker HC. T cell fate following Salmonella infection is determined by a STING-IRF1 signaling axis in mice. Commun Biol. 2019 Dec 11;2:464. (* Co-first author)
  5. Tanaka O, Omatsu T, Kariya S, Maejima R, Taniguchi T, Ono K, Kunishima Y, Matsuo M. Usefulness of diffusion-weighted magnetic resonance imaging for evaluating the effect of hemostatic radiotherapy for unresectable gastric cancer. Clin J Gastroenterol. 2019 Jun;12(3):269-273.
  6. Handa O, Takayama S, Mukai R, Suyama Y, Majima A, Fukui A, Omatsu T, Naito Y. A review of the mechanism and prophylaxis of acetyl salicylic acid-induced injury of the small intestine. Free Radic Res. 2018 Apr 3:1-5.
  7. Woo M, Patterson EK, Cepinskas G, Clarson C, Omatsu T, Fraser DD. Dynamic Regulation of Plasma Matrix Metalloproteinases in Human Diabetic Ketoacidosis. Pediatr Res. 2016 Feb;79(2):295-300.
  8. Lammers KM, Chieppa M, Liu L, Liu S, Omatsu T, Janka-Junttila M, Casolaro V, Reinecker HC, Parent CA, Fasano A. Gliadin Induces Neutrophil Migration via Engagement of the Formyl Peptide Receptor, FPR1. PLoS One. 2015 Sep 17;10(9):e0138338.
  9. Omatsu T, Cepinskas G, Clarson C, Patterson EK, Alharfi IM, Summers K, Couraud PO, Romero IA, Weksler B, Fraser DD. CXCL1/CXCL8 (GROα/IL-8) in human diabetic ketoacidosis plasma facilitates leukocyte recruitment to cerebrovascular endothelium in vitro. Am J Physiol Endocrinol Metab. 2014 May 1;306(9):E1077-84.
  10. Close TE, Cepinskas G, Omatsu T, Rose KL, Summers K, Patterson EK, Fraser DD. Diabetic ketoacidosis elicits systemic inflammation associated with cerebrovascular endothelial cell dysfunction. Microcirculation. 2013 Aug;20(6):534-43.
  11. Ogawa K, Omatsu T, Matsumoto C, Tsuchiya N, Yamamoto M, Naito Y, Yoshikawa T. Protective effect of the Japanese traditional medicine juzentaihoto on myelosuppression induced by the anticancer drug TS-1 and identification of a potential biomarker of this effect. BMC Complement Altern Med. 2012 Aug 9;12:118.
  12. Omatsu T, Naito Y, Handa O, Mizushima K, Hayashi N, Qin Y, Harusato A, Hirata I, Kishimoto E, Okada H, Uchiyama K, Ishikawa T, Takagi T, Yagi N, Kokura S, Ichikawa H, Yoshikawa T. Reactive oxygen species-quenching and anti-apoptotic effect of polaprezinc on indomethacin-induced small intestinal epithelial cell injury. J Gastroenterol. 2010 Jul;45(7):692-702.
  13. Naito Y, Takagi T, Okada H, Omatsu T, Mizushima K, Handa O, Kokura S, Ichikawa H, Fujiwake H, Yoshikawa T. Identification of inflammation-related proteins in a murine colitis model by 2D fluorescence difference gel electrophoresis and mass spectrometry. J Gastroenterol Hepatol. 2010 May;25 Suppl 1:S144-8.
  14. Takagi T, Naito Y, Mizushima K, Akagiri S, Suzuki T, Hirata I, Omatsu T, Handa O, Kokura S, Ichikawa H, Yoshikawa T. Inhalation of Carbon Monoxide Ameliorates TNBS-Induced Colitis in Mice Through the Inhibition of TNF-alpha Expression. Dig Dis Sci. 2010 Oct;55(10):2797-804.
  15. Uchiyama K, Naito Y, Takagi T, Mizushima K, Hayashi N, Harusato A, Hirata I, Omatsu T, Handa O, Ishikawa T, Yagi N, Kokura S, Yoshikawa T. Carbon monoxide enhance colonic epithelial restitution via FGF15 derived from colonic myofibroblasts. Biochem Biophys Res Commun. 2010 Jan 1;391(1):1122-6.
  16. Omatsu T, Naito Y, Handa O, Hayashi N, Mizushima K, Qin Y, Hirata I, Adachi S, Okayama T, Kishimoto E, Takagi T, Kokura S, Ichikawa H, Yoshikawa T. Involvement of reactive oxygen species in indomethacin-induced apoptosis of small intestinal epithelial cells. J Gastroenterol. 2009;44 Suppl 19:30-4.
  17. Hirata I, Naito Y, Handa O, Hayashi N, Mizushima K, Adachi S, Omatsu T, Okayama T, Kishimoto E, Ichikawa H, Takagi T, Kokura S, Otaka M, Yoshikawa T. Heat-shock protein 70-overexpressing gastric epithelial cells are resistant to indomethacin-induced apoptosis. Digestion. 2009;79(4):243-50.
  18. Omatsu T, Naito Y, Handa O, Hayashi N, Mizushima K, Qin Y, Hirata I, Okayama T, Adachi S, Kishimoto E, Takagi T, Kokura S, Ichikawa H, Yoshikawa T. Anti-apoptotic effect of vitamin E on indomethacin-induced intestinal epithelial cell injury. J Clin Biochem Nutr. 2008 Jul;43 Suppl 1:433-5.
  19. Hamaguchi M, Kojima T, Takeda N, Nakagawa T, Taniguchi H, Fujii K, Omatsu T, Nakajima T, Sarui H, Shimazaki M, Kato T, Okuda J, Ida K. The metabolic syndrome as a predictor of nonalcoholic fatty liver disease. Ann Intern Med. 2005 Nov 15;143(10):722-8.

〒602-8566 京都市上京区河原町通広小路上る梶井町465番地 京都府立医科大学消化器内科
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