専　門

• 消化器病学
• 消化器内視鏡学
• 消化器癌の発生と進展
• 消化器癌発癌の化学予防

所属学会

• 日本内科学会　総合内科専門医・指導医
• 日本消化器病学会　専門医・指導医（学会評議員）
• 日本消化器内視鏡学会　専門医・指導医（社団評議員）
• 日本食道学会　食道科認定医（評議員）
• 日本胃癌学会（代議員）
• PEG・在宅医療学会（代議員）
• 日本消化管学会　胃腸科認定医・専門医・指導医
• 日本ヘリコバクター学会　ピロリ菌感染症認定医
• 日本カプセル内視鏡学会　専門医・指導医
• 日本癌学会
• 日本臨床腫瘍学会
• 日本病理学会
• 日本門脈圧亢進症学会
• 日本アルコール・薬物医学会
• American Gastroenterological Association、International Member
• American Association for Cancer Research、Active Member

資　格

• 日本内科学会　総合内科専門医・指導医
• 日本消化器病学会　専門医・指導医
• 日本消化器内視鏡学会専門医・指導医
• 日本消化管学会胃腸科専門医・指導医
• 日本カプセル内視鏡学会指導医
• 日本がん治療認定医機構がん治療認定医
• 日本医師会認定産業医
• 厚生労働省認定臨床修練指導医

業　績

1. Hirose R, Daidoji T, Naito Y, Dohi O, Yoshida N, Yasuda H, Konishi H, Nakaya T, Itoh Y. A New Ex Vivo Model for the Evaluation of Endoscopic Submucosal Injection Material Performance. J Vis Exp. 2018 Oct 19;(140). doi: 10.3791/58029. PubMed PMID: 30394381
2. Horii Y, Dohi O, Naito Y, Takayama S, Ogita K, Terasaki K, Nakano T, Majima A, Yoshida N, Kamada K, Uchiyama K, Ishikawa T, Takagi T, Handa O, Konishi H, Yagi N, Yanagisawa A, Itoh Y. Efficacy of Magnifying Narrow Band Imaging for Delineating Horizontal Margins of Early Gastric Cancer. Digestion. 2018 Nov 13:1-7. doi: 10.1159/ 000494053. [Epub ahead of print] PubMed PMID: 30423568.
3. Toyokawa Y, Takagi T, Uchiyama K, Mizushima K, Inoue K, Ushiroda C, Kashiwagi S, Nakano T, Hotta Y, Tanaka M, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K,Ishikawa T, Handa O, Konishi H, Naito Y, Itoh Y. Ginsenoside Rb1 promotes intestinal epithelial wound healing through extracellular signal-regulated kinase and Rho signaling. J Gastroenterol Hepatol. 2018 Nov 5. doi:10.1111/jgh.14532. [Epub ahead of print] PubMed PMID: 30394577.
4. Uchiyama K, Naito Y, Yagi N, Mizushima K, Higashimura Y, Hirai Y, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Handa O, Ishikawa T, Takagi T, Konishi H, Nonaka D, Asada K, Lee LJ, Tanaka K, Kuriu Y, Nakanishi M, Otsuji E, Itoh Y. Selected reaction monitoring for colorectal cancer diagnosis using a set of five serum peptides identified by BLOTCHIP(®)-MS analysis. J Gastroenterol. 2018. Nov;53(11):1179-1185. doi: 10.1007/ s00535-018-1448-0. Epub 2018 Mar 1. PubMed PMID: 29497816.
5. Dohi O, Yoshida N, Terasaki K, Azuma Y, Ishida T, Kitae H, Matsumura S, Ogita K, Takayama S, Mizuno N, Nakano T, Hirose R, Inoue K, Kamada K, Uchiyama K, Ishikawa T, Takagi T, Kishimoto M, Konishi H, Naito Y, Itoh Y. Efficacy of Clutch Cutter for Standardizing Endoscopic Submucosal Dissection for Early Gastric Cancer: A Propensity Score-Matched Analysis. Digestion. 2018 Dec 6:1-9. doi: 10.1159/000495287. [Epub ahead of print] PubMed PMID: 30522097.
6. Dohi O, Yagi N, Naito Y, Fukui A, Gen Y, Iwai N, Ueda T, Yoshida N, Kamada K, Uchiyama K, Takagi T, Konishi H, Yanagisawa A, Itoh Y. Blue laser imaging-bright improves the real-time detection rate of early gastric cancer: a randomized controlled study. Gastrointest Endosc. 2019 Jan;89(1):47-57. doi: 10.1016/j.gie.2018.08.049. Epub 2018 Sep 4. PubMed PMID: 30189197.
7. Hirose R, Nakaya T, Naito Y, Daidoji T, Dohi O, Yoshida N, Yasuda H, Konishi H, Itoh Y. Identification of the critical viscoelastic factor in the performance of submucosal injection materials. Mater Sci Eng C Mater Biol Appl. 2019 Jan 1; 94: 909-919. doi: 10.1016/ j.msec.2018.10. 051. Epub 2018 Oct 12. PubMed PMID: 30423779.
8. Ota T, Ishikawa T, Endo Y, Matsumura S, Yoshida J, Yasuda T, Okayama T, Inoue K, Dohi O, Yoshida N, Sakamoto N, Kamada K, Uchiyama K, Takagi T, Konishi H, Konishi H, Shiozaki A, Fujiwara H, Kishimoto M, Naito Y, Itoh Y. Skeletal muscle mass as a predictor of the response to neo-adjuvant chemotherapy in locally advanced esophageal cancer. Med Oncol. 2019 Jan 2;36(2):15. doi: 10.1007/s12032-018-1242-0. PubMed PMID: 30600347.
9. Takagi T, Naito Y, Inoue R, Kashiwagi S, Uchiyama K, Mizushima K, Tsuchiya S, Dohi O, Yoshida N, Kamada K, Ishikawa T, Handa O, Konishi H, Okuda K, Tsujimoto Y, Ohnogi H, Itoh Y. Differences in gut microbiota associated with age, sex, and stool consistency in healthy Japanese subjects. J Gastroenterol. 2019 Jan;54(1): 53-63. doi: 10.1007/s00535-018-1488-5. Epub 2018 Jun 20. Erratum in: J Gastroenterol. 2018 Sep 6;:. PubMed PMID: 29926167.
10. Abdul Rani R, Yoshida N, Murakami T, Ogiso K, Hirose R, Inada Y, Konishi H, Naito Y, Kishimoto M, Ando T, Itoh Y. A circumferential rectal superficial neoplasm resected with endoscopic submucosal dissection using the pocket-creation method. Endosc Int Open. 2018 Apr;6(4):E484-E488. doi: 10.1055/s-0044-101349. Epub 2018 Mar 29.
11. Ishikawa T, Okayama T, Sakamoto N, Ideno M, Oka K, Enoki T, Mineno J, Yoshida N, Katada K, Kamada K, Uchiyama K, Handa O, Takagi T, Konishi H, Kokura S, Uno K, Naito Y, Itoh Y. Phase I clinical trial of adoptive transfer of expanded natural killer cells in combination with IgG1 antibody in patients with gastric or colorectal cancer. Int J Cancer. 2018 Jun 15;142(12):2599-2609. doi: 10.1002/ijc.31285.
12. Iwai N, Handa O, Naito Y, Dohi O, Okayama T, Yoshida N, Kamada K, Uchiyama K, Ishikawa T, Takagi T, Konishi H, Itoh Y. Stenotic Ischemic Enteritis with Concomitant Hepatic Portal Venous Gas and Pneumatosis Cystoides Intestinalis. Intern Med. 2018 Jul15; 57(14): 1995-1999. doi: 10.2169/internalmedicine.0367-17. Epub 2018 Feb 28.
13. Iwai N, Yasui K, Tomie A, Gen Y, Terasaki K, Kitaichi T, Soda T, Yamada N, Dohi O, Seko Y, Umemura A, Nishikawa T, Yamaguchi K, Moriguchi M, Konishi H, Naito Y, Itoh Y. Oncogenic miR-96-5p inhibits apoptosis by targeting the caspase-9 gene in hepatocellular carcinoma. Int J Oncol. 2018 Jul;53(1):237-245. doi: 10.3892/ijo.2018.4369. Epub 2018 Apr 12.
14. Yoshida N, Naito Y, Yasuda R, Murakami T, Hirose R, Ogiso K, Inada Y, Konishi H, Rani RA, Kishimoto M, Konishi E, Nakanishi M, Itoh Y. The efficacy of the pocket-creation method for cases with severe fibrosis in colorectal endoscopic submucosal dissection. Endosc Int Open. 2018 Aug;6(8):E975-E983. doi: 10.1055/a-0593-5818. Epub 2018 Aug 3.
15. Dohi O, Yagi N, Naito Y, Fukui A, Gen Y, Iwai N, Ueda T, Yoshida N, Kamada K, Uchiyama K, Takagi T, Konishi H, Yanagisawa A, Itoh Y. Blue laser imaging-bright improves real-time detection rate of early gastric cancer: a randomized controlled study. Gastrointest Endosc. 2018 Sep 3. pii: S0016-5107(18)33008-6. doi: 10.1016/j.gie.2018.08.049. [Epub ahead of print]
16. Iwai N, Dohi O, Naito Y, Inada Y, Fukui A, Takayama S, Ogita K, Terasaki K, Nakano T, Ueda T, Okayama T, Yoshida N, Katada K, Kamada K, Uchiyama K, Ishikawa T, Handa O, Takagi T, Konishi H, Yagi N, Itoh Y. Impact of the Charlson comorbidity index and prognostic nutritional index on prognosis in patients with early gastric cancer after endoscopic submucosal dissection. Dig Endosc. 2018 Sep;30(5):616-623. doi: 10.1111/den.13051. Epub 2018 Apr 11.
17. Kitaichi T, Dohi O, Fujita Y, Majima A, Horii Y, Yasuda-Onozawa Y, Suzuki K, Tomie A, Okayama T, Yoshida N, Kamada K, Uchiyama K, Ishikawa T, Handa O, Konishi H, Kishimoto M, Yagi N, Naito Y, Yanagisawa A, Itoh Y. Clinical and Pathological Challenges in the Diagnosis of Gastric-Type Differentiated Adenocarcinoma in the Stomach: A Study of Endoscopic Submucosal Dissection Cases. Digestion. 2018 Sep 18:1-9. doi: 10.1159/000493095. [Epub ahead of print]
18. Kimura-Tsuchiya R, Dohi O, Fujita Y, Yagi N, Majima A, Horii Y, Kitaichi T, Onozawa Y, Suzuki K, Tomie A, Okayama T, Yoshida N, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Handa O, Konishi H, Kishimoto M, Naito Y, Yanagisawa A, Itoh Y. Magnifying Endoscopy with Blue Laser Imaging Improves the Microstructure Visualization in Early Gastric Cancer: Comparison of Magnifying Endoscopy with Narrow-Band Imaging. 2017;2017:8303046. doi: 10.1155/2017/8303046. Epub 2017 Aug 30.
19. Hirose R, Nakaya T, Naito Y, Daidoji T, Watanabe Y, Yasuda H, Konishi H, Itoh Y. Viscosity is an important factor of resistance to alcohol-based disinfectants by pathogens present in mucus. Sci Rep. 7(1):13186, 2017.
20. Yasuda-Onozawa Y, Handa O, Naito Y, Ushiroda C, Suyama Y, Toyokawa Y, Murakami T, Yasuda T, Ueda T, Majima A, Hotta Y, Doi T, Tanaka M, Horii Y, Higashimura Y, Mizushima K, Morita M, Uehara Y, Horie H, Fukui A, Dohi O, Okayama T, Yoshida N, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Konishi H, Itoh Y. Rebamipide upregulates mucin secretion of intestinal goblet cells via Aktphosphorylation. Mol med rep. 16(6):8216-8222, 2017. 2017 Dec
21. Yoshida N, Naito Y, Yasuda R, Murakami T, Ogiso K, Hirose R, Inada Y, Dohi O, Okayama T, Kamada K, Uchiyama K, Ishikawa T, Handa O, Konishi H, Rani RA, Itoh Y. A novel lens cleaner to prevent water drop adhesions during colonoscopy and esophagogastroduodenoscopy. Endosc Int Open 5(12):E1235-E1241, 2017.
22. Ishikawa T, Okayama T, Sakamoto N, Ideno M, Oka K, Enoki T, Mineno J, Yoshida N, Katada K, Kamada K, Uchiyama K, Handa O, Takagi T, Konishi H, Kokura S, Uno K, Naito Y, Itoh Y. Phase I clinical trial of adoptive transfer of expanded natural killer cells in combination with IgG1 antibody in patients with gastric or colorectal cancer. Int J Cancer. 2018 Jan 31.
23. Takagi T, Naito Y, Inoue R, Kashiwagi S, Uchiyama K, Mizushima K, Tsuchiya S, Okayama T, Dohi O, Yoshida N, Kamada K, Ishikawa T, Handa O, Konishi H, Okuda K, Tsujimoto Y, Ohnogi H, Itoh Y. The influence of long-term use of proton pump inhibitors on the gut microbiota: an age-sex-matched case-control study. J Clin Biochem Nutr. 62(1): 100-105, 2018.
24. Ueda T, Takagi T, Katada K, Iida T, Mizushima K, Dohi O, Okayama T, Yoshida N, Kamada K, Uchiyama K, Handa O, Ishikawa T, Konishi H, Naito Y, Nagasaki Y, Itoh Y. The protective effect of orally administered redox nanoparticle on intestinal ischemia-reperfusion injury in mice. Biochem Biophys Res Commun. 495(2): 2044-2049, 2018.
25. Iwai N, Handa O, Naito Y, Dohi O, Okayama T, Yoshida N, Kamada K, Uchiyama K, Ishikawa T, Takagi T, Konishi H, Itoh Y. Stenotic ischemic enteritis with concomitant hepatic portal venous gas and pneumatosis cystoides intestinalis: a case report. Intern med. 2018 Feb 28. doi: 10.2169/internalmedicine.0367-17. [Epub ahead of print] PubMed PMID: 29491303.
26. Hirose R, Nakaya T, Naito Y, Daidoji T, Yasuda H, Konishi H, Itoh Y. Development of a new ex vivo model for evaluation of endoscopic submucosal injection materials performance. J Mech Behav Biomed Mater 79:219-225, 2018.
27. Iwai N, Dohi O, Naito Y, Inada Y, Fukui A, Takayama S, Ogita K, Terasaki K, Nakano T, Ueda T, Okayama T, Yoshida N, Katada K, Kamada K, Uchiyama K, Ishikawa T, Handa O, Takagi T, Konishi H, Yagi N, Itoh Y. Impact of the Charlson comorbidity index and prognostic nutritional index on prognosis in patients with early gastric cancer after endoscopic submucosal dissection. Dig Endosc. 2018 Mar 13
28. Suyama Y, Handa O, Naito Y, Takayama S, Mukai R, Ushiroda C, Majima A, Yasuda-Onozawa Y, Higashimura Y, Fukui A, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Uchiyama K, Ishikawa T, Takagi T, Konishi H, Itoh Y. Mucus reduction promotes acetyl salicylic acid-induced small intestinal mucosal injury in rats. Biochem Biophys Res Commun. 498(1):228-233, 2018.
29. Uchiyama K, Naito Y, Yagi N, Mizushima K, Higashimura Y, Hirai Y, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Handa O, Ishikawa T, Takagi T, Konishi H, Nonaka D, Asada K, Lee LJ, Tanaka K, Kuriu Y, Nakanishi M, Otsuji E, Itoh Y. Selected reaction monitoring for colorectal cancer diagnosis using a set of five serum peptides identified by BLOTCHIP(®)-MS analysis. J Gastroenterol. 2018 Mar 1.
30. Hirose R, Nakaya T, Naito Y, Daidoji T, Watanabe Y, Yasuda H, Konishi H, Itoh Y. Mechanism of Human Influenza Virus RNA Persistence and Virion Survival in Feces: Mucus Protects Virions From Acid and Digestive Juices. J Infectious Dis, 216: 105., 2017.
31. Yoshida N, Naito Y, Murakami T, Hirose R, Ogiso K, Inada Y, Dohi O, Kamada K, Uchiyama K, Handa O, Konishi H, Siah KTH, Yagi N, Fujita Y, Kishimoto M, Yanagisawa A, Itoh Y. Linked color imaging improves the visibility of colorectal polyps: a video study. Endoscopy International Open 2017; 05: E518.
32. Fujita Y, Kishimoto M, Dohi O, Kamada K, Majima A, Kimura-Tsuchiya R, Yagi N, Konishi H, Naito Y, Harada Y, Tanaka H, Konishi E, Sugai T, Yanagisawa A. How to adjust endoscopic findings to histopathological findings of the stomach: a “histopathology‑oriented” correspondence method helps to understand endoscopic findingsGastric Cancer, 2017.
33. Majima A, Handa O, Naito Y, Suyama Y, Onozawa Y, Higashimura Y, Mizushima K, Morita M, Uehara Y, Horie H, Iida T, Fukui A, Dohi O, Okayama T, Yoshida N, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Konishi H, Yasukawa Z, Tokunaga M, Okubo T, Itoh Y. Real-time monitoring of trans-epithelial electrical resistance in cultured intestinal epithelial cells: the barrier protection of water-soluble dietary fiber. J Dig Dis. 2017 Jan 31. doi: 10.1111/1751-2980.12456. [Epub ahead of print]
34. Hirose R, Yoshida N, Murakami T, Ogiso K, Inada Y, Dohi O, Okayama T, Kamada K, Uchiyama K, Handa O, Ishikawa T, Konishi H, Naito Y, Fujita Y, Kishimoto M, Yanagisawa A, Itoh Y. Histopathological analysis of cold snare polypectomy and its indication for colorectal polyps 10-14mm in diameter. Dig Endosc. 2017 Feb 3. doi: 10.1111/den.12825. [Epub ahead of print]
35. Komaki K, Kusaba T, Tanaka M, Kado H, Shiotsu Y, Matsui M, Shiozaki A, Nakano H, Ishikawa T, Fujiwara H, Konishi H, Itoh Y, Matoba S, Tamagaki K. Lower blood pressure and risk of cisplatin nephrotoxicity: a retrospective cohort study. BMC Cancer. 2017 Feb 20;17(1):144. doi: 10.1186/s12885-017-3135-6.
36. Uchiyama K, Takagi T, Kashiwagi S, Toyokawa Y, Tanaka M, Hotta Y, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Ishikawa T, Handa O, Konishi H, Kishimoto M, Yagi N, Naito Y, Itoh Y. Assessment of endoscopic mucosal healing of ulcerative colitis using linked colour imaging, a novel endoscopic enhancement system. J Crohns Colitis. 2017 Feb 22. doi: 10.1093/ecco-jcc/jjx026. [Epub ahead of print]
37. Tomie A, Dohi O, Yagi N, Kitae H, Majima A, Horii Y, Kitaichi T, Onozawa Y, Suzuki K, Kimura-Tsuchiya R, Okayama T, Yoshida N, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Handa O, Konishi H, Naito Y, Itoh Y. Blue Laser Imaging-Bright Improves Endoscopic Recognition of Superficial Esophageal Squamous Cell Carcinoma. Gastroenterol Res Pract. 2016;2016:6140854. Epub 2016 Sep 22.
38. Uchiyama K, Yagi N, Mizushima K, Higashimura Y, Hirai Y, Okayama T, Yoshida N, Katada K, Kamada K, Handa O, Ishikawa T, Takagi T, Konishi H, Kuriu Y, Nakanishi M, Otsuji E, Itoh Y, Naito Y. Serum metabolomics analysis for early detection of colorectal cancer. J Gastroenterol. 2016 Sep 20. [Epub ahead of print]
39. Tsujimoto H, Yamanaka K, Miyamoto H, Horii T, Abe R, Tanaka S, Torii, Ozamoto Y, Takagi T, Takimoto K, Torii T, Konishi H, Takamori H, Hagiwara A. A basic study of the effect of the shielding method with polyglycolic acid fabric and fibrin glue after endoscopic submucosal dissection. Endosc Int Open. 2016 Dec;4(12):E1298-E1304.
40. Ishikawa T, Yasuda T, Doi T, Okayama T, Sakamoto N, Gen Y, Dohi O, Yoshida N, Kamada K, Uchiyama K, Handa O, Takagi T, Konishi H, 　Yagi N, Kokura S, Naito Y, Itoh Y. The amino acid-rich elemental diet Elental® preserves lean body mass during chemo- or chemoradiotherapy for esophageal cancer. Oncol Rep. 2016 Jun 15. doi: 10.3892/or.2016.4877.
41. Horii Y, Uchiyama K, Toyokawa Y, Hotta Y, Tanaka M, Yasukawa Z, Tokunaga M, Okubo T, Mizushima K, Higashimura Y, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Handa O, Ishikawa T, Takagi T, Konishi H, Naito Y, Itoh Y. Partially hydrolyzed guar gum enhances colonic epithelial wound healing via activation of RhoA and ERK1/2. Food Funct. 2016 Jun 15. [Epub ahead of print]
42. Gen Y, Yasui K, Kitaichi T, Iwai N, Terasaki K, Dohi O, Hashimoto H, Fukui H, Inada Y, Fukui A, Jo M, Moriguchi M, Nishikawa T, Umemura A, Yamaguchi K, Kon ishi H, Naito Y, Itoh Y.ASPP2 suppresses invasion and TGF-β1-induced epithelial-mesenchymal transition by inhibiting Smad7 degradation mediated by E3 ubiquitin ligase ITCH in gastric cancer. Cancer Lett. 2017 Jul 10;398:52-61. doi: 10.1016/j.canlet. 2017.04.002. Epub 2017 Apr 9.
43. Majima A, Handa O, Naito Y, Dohi O, Okayama T, Yoshida N, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Konishi H, Yagi N, Itoh Y. Early-Stage Gastric Cancer Can Be Found in Improved Atrophic Mucosa over Time from Successful Helicobacter pylori Eradication. Digestion. 2017;95(3):194-200. doi: 10.1159/000460245. Epub 2017 Mar 14.
44. Dohi O, Yagi N, Majima A, Horii Y, Kitaichi T, Onozawa Y, Suzuki K, Tomie A, Kimura-Tsuchiya R, Tsuji T, Yamada N, Bito N, Okayama T, Yoshida N, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Handa O, Konishi H, Naito Y, Yanagisawa A, Itoh Y. Diagnostic ability of magnifying endoscopy with blue laser imaging for early gastric cancer: a prospective study. Gastric Cancer. 2017 Mar;20(2):297-303. doi: 10.1007/s10120-016-0620-6.
45. Dohi O, Yagi N, Onozawa Y, Kimura-Tsuchiya R, Majima A, Kitaichi T, Horii Y, Suzuki K, Tomie A, Okayama T, Yoshida N, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Handa O, Konishi H, Naito Y, Itoh Y.Linked color imaging improves endoscopic diagnosis of active Helicobacter pylori infection. Endosc Int Open. 4(7): 800-80 5, 2016.
46. Yoshida N, Naito Y, Murakami T, Hirose R, Ogiso K, Inada Y, Dohi O, Okayama T, Kamada K, Uchiyama K, Ishikawa T, Handa O, Konishi H, Siah KT, Yagi N, Itoh Y. Safety and Efficacy of a Same-Day Low-Volume 1 L PEG Bowel Preparation in Colonoscopy for the Elderly People and People with Renal Dysfunction. Dig Dis Sci. 2016 Aug 3. [Epub ahead of print]
47. Yoshida N, Naito Y, Siah KT, Murakami T, Ogiso K, Hirose R, Inada Y, Inoue K, Konishi H, Kugai M, Morimoto Y, Hasegawa D, Kanemasa K, Wakabayashi N, Yagi N, Yanagisawa A, Itoh Y. High incidence of metachronous advanced adenoma and cancer after endoscopic resection of colon polyps ≥20 mm in size. Dig Endosc. 28(2):194-202, 2016.
48. Okayama T, Ishikawa T, Sugatani K, Yoshida N, Kokura S, Matsuda K, Tsukamoto S, Ihara N, Kuriu Y, Nakanishi M, Nakamura T, Kamada K, Katada K, Uchiyama K, Takagi T, Handa O, Konishi H, Yagi N, Naito Y, Otsuji E, Hosoi H, Miki T, Itoh Y. Hypersensitivity Reactions to Oxaliplatin: Identifying the Risk Factors and Judging the Efficacy of a Desensitization Protocol. Clin Ther 37:1259-1269, 2015.
49. Yoshida N, Naito Y, Ho KT, Murakami T, Ogiso K, Hirose R, Inada Y, Inoue K, Konishi H, Kugai M, Morimoto Y, Hasegawa D, Kanemasa K, Wakabayashi N, Yagi N, Yanagisawa A, Itoh Y. Risk of lens cludness during colorectal endoscopi submucosal dissection and ability of a novel lens cleaner to maintain and restore endoscopic view. Dig Endosc27(3):609-617, 2015.
50. Yoshida N, Naito Y, Ho KT, Murakami T, Ogiso K, Hirose R, Inada Y, Inoue K, Konishi H, Kugai M, Morimoto Y, Hasegawa D, Kanemasa K, 　Wakabayashi N, Yagi N, Yanagisawa A, Itoh Y. High incidence of metachronous advanced adenoma and cancer after endoscopic resection of colon polyps larger than or equal to 20mm in size. Dig Endosc Epub ahead. 1011-1111 2015.
51. Kanbayashi Y, Konishi H Predictie Factors for NSAIDs-related Gastrointestinal Toxicity: Can COX-2 Selective Inhibitors Can Prevent it? Hepato-Gastroenterology 62: 787-789, 2015.
52. Ogiso K, Yoshida N, Siah KT, Murakami T, Hirose R, Inada Y, Dohi O, Okayama T, Kamada K, Uchiyama K, Ishikawa T, Handa O, Konishi H, Naito Y, Yanagisawa A, Itoh Y.New-generation narrow band imaging improves visibility of polyps: a colonoscopy video evaluation study. J. Gastroetnerol Epub ahead, Jan 16. 2015.
53. Fukumoto K, Konishi H, Soga K, Miyawaki K, Okano H, Minami M, Wakabayashi N, Mitsufuji S, Yoshida N, Takagi T, Yagi N, Naito Y, Kataoka K, Yoshikawa T. Successful endoscopic injection sclerotherapy of high-risk gastroesophageal varices in a cirrhotic patient with hemophilia A. Gastroenterol Res Pract. 2010:518260.
54. Yoshida N, Yagi N, Inada Y, Kugai M, Okayama T, Kamada K, Katada K, Uchiyama K, Ishikawa T, Handa O, Takagi T, Konishi H, Kokura S, Yanagisawa A, Naito Y.The ability of a novel blue laser imaging system for the diagnosis of colorectal polyps. Dig Endosc 26(2):250-258, 2014
55. Ishikawa T, Kokura S, Enoki T, Sakamoto N, Okayama T, Ideno M, Mineno J, Uno K, Yoshida N, Kamada K, Katada K, Uchiyama K, Handa O, Takagi T, Konishi H, Yagi N, Naito Y, Itoh Y, Yoshikawa T. Phase I clinical trial of fibronectin CH296-stimulated T cell therapy in patients with advanced cancer PLoS One 9(1) e83786, 2014.
56. Uchiyama K, Takagi T, Iwamoto Y, Kondo N, Okayama T, Yoshida N, Kamada K, Katada K, Handa O, Ishikawa T, Yasuda H, Sakagami J, Konishi H, Yagi N, Naito Y, Itoh Y. New genetic biomarkers predicting azathioprine blood concentrations in combination therapy with 5-aminosalicylic acid. PLoS One 9(4) e95080, 2014.
57. Fukuda W, Takagi T, Katada K, Mizushima K, Okayama T, Yoshida N, Kamada K, Uchiyama K, Ishikawa T, Handa O, Konishi H, Yagi N, Ichikawa H, Yoshikawa T, Cepinskas G, Naito Y, Itoh Y. Anti-inflammatory Effects of Carbon Monoxide-Releasing Molecule on Trinitrobenzene Sulfonic Acid-Induced Colitis in Mice. Dig Dis Sci 59: 1142-1151, 2014.
58. Yoshida N, Naito Y, Hirose R, Ogiso K, Inada Y, Fernandopulle N, Kamada K, Katada K, Uchiyama K, Handa O, Takagi T, Konishi H, Yagi N, Wakabayash N, Yanagisawa A, Itoh Y. Prevention of Colonic Spasm Using L-Menthol in Colonoscopic Examination. Int J Colorectal Dis 29: 579-583, 2014.
59. Inoue K, Dohi O, Gen Y, Jo M, Mazaki T, Tokita K, Yoshida N, Okayama T, Kamada K, Katada K, Uchiyama K, Ishikawa T, Handa O, Takagi T, Konishi H, Wakabayashi N, Yagi N, Naito Y, Itoh Y. L-menthol improves adenoma detection rate during colonoscopy: a randomized trial Endoscopy 46: 196-202, 2014.
60. Kitano M, Yamashita Y, Tanaka K, Konishi H, Yazumi S, Nakai, Y, Nishiyama O, Uehara H, Mitoro A, Sanuki T, Takaoka M, Koshitani T, Arisaka Y, Shiba M, Hoki N, Sato H, Sasaki Y, Hasegawa K, Kawabata H, Okabe Y, Mukai H.Covered Self-Expandable Metal Stents With an Anti-Migration System Improve Patency Duration Without Increased Complications Compared with Uncovered Stents for Distal Biliary Obstruction Caused by Pancreatic Carcinoma: A Randomized Multicenter Trial. Am J Gastroenterol 108(11), 1713-1722, 2013.
61. Handa O, Naito Y, Okayama T, Yoshida N, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Konishi H, Yagi N, Kokura S, Yoshikawa T. Endoscopic diagnosis of small intestinal diseases. Clin J Gastroenterol 6(2): 94-98, 2013.
62. Inada Y, Yoshida N, Kugai M, Kamada K, Katada K, Uchiyama K, Handa O, Takagi T, Konishi H, Yagi N, Naito Y, Wakabayashi N, Yanagisawa A, Itoh Y. Prediction and treatment of difficult cases in colorectal endoscopic submucosal dissection. Gastroenterol Res Pract 2013, 523084, 2013.
63. Kugai M, Uchiyama K, Tsuji T, Yoriki H, Fukui A, Qin Y, Higashimura Y, Mizushima K, Yoshida N, Katada K, Kamada K, Handa O, Takagi T, Konishi H, Yagi N, Yoshikawa T, Shirasaka Y, Tamai I, Naito Y, Itoh Y. MDR1 is Related to Intestinal Epithelial Injury Induced by Acetylsalicylic Acid. Cell Physiol Biochem 32: 942-950, 2013.
64. Tsuji T, Naito Y, Takagi T, Kugai M, Yoriki H, Horie R, Fukui A, Mizushima K, Hirai Y, Katada K, Kamada K, Uchiyama K, Handa O, Konishi H, Yagi N, Ichikawa H, Yanagisawa R, Suzuki JS, Takano H, Satoh M, Yoshikawa T. Role of metallothionein in murine experimental colitis. Int J Mol Med 31: 1037-1046, 2013.
65. Yoshida N, Yagi N, Inada Y, Kugai M, Kamada K, Katada K, Uchiyama K Ishikawa T, Takagi T, Handa O, Konishi H, Kokura S, Inoue K, Wakabayashi N, Abe Y, Yanagisawa A, Naito Y. Possibility of ex vivo animal training model for colorectal endoscopic submucosal dissection Int J Colorectal Dis 28: 49-56, 2013.
66. Ishikawa T, Kokura S, Sakamoto N, Okajima M, Matsuyama T, Sakai H Okumura Y, Adachi S, Yoshida N, Uchiyama K, Handa O, Takagi T, Konishi H, Wakabayashi N, Yagi N, Ando T, Uno K, Naito Y, Yoshikawa T. Relationship between circulating cytokine levels and physical or psychological functioning in patients with advanced cancer. Clinical Biochemistry 45: 207-211, 2012.
67. Imaizumi K, Harada Y, Wakabayashi N, Yamaoka Y, Konishi H, Dai P, Tanaka H, Takmatsu T.97．Dual-wavelength excitation of mucosal autofluorescence for precise detection of diminutive colonic adenomasGastrointestinal Endsc 75(1): 110-117, 2012.
68. Konishi H, Okano H, Fukumoto K, Miyawaki K, Wakabayashi N, Yagi N, Naito Y, Yoshikawa T. Usefulness of a novel observation method using a small- diameter rigid telescope through the gastrostomy catheter at exchange. Dig. Endosc, 24(4): 243-6, 2012.
69. Yoshida N, Naito Y, Inada Y, Kugai M, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Hand O, Konishi H, Yagi N, Kokura S, Wakabayashi N, Yanagisawa A, Yoshikawa T. Endoscopic mucosal resection with 0.13% hyaluronic acid solution for colorectal polyps less than 20mm: A randomized controlled trial. J Gastreonterol Hepatol 27: 1377-1383, 2012.
70. Yoshida N, Naito Y, Inada Y, Kugai M, Inoue K, Uchiyama K, Handa O, Takagi T, Konishi H, Yagi N, Morimoto Y, Wakabayashi N, Yanagisawa A, Yoshikawa T. The detection of surface patterns by flexible spectral imaging color enhancement without magnification for diagnosis of colorectal polyps. Int J Colorectal Dis 27(5): 605-611, 2012.
71. Inoue K, Wakabayashi N, Fukumoto K, Yamada S, Bito N, Yoshida N, Katada K, Uchiyama K, Ishikawa T, Handa O, Takagi T, Konishi H, Yagi N, Kokura S, Kishimoto M, Yanagisawa A, Naito Y. Toxic megacolon associated with cytomegalovirus infection in a patient with steroid-naïve ulcerative colitis. Intern Med 51(19): 2739-2743, 2012.
72. Dohi O, Yagi N, Wada T, Yamada N, Bito N, Yamada S, Gen Y, Yoshida N, Uchiyama K, Ishikawa T, Takagi T, Handa O, Konishi H, Wakabayashi N, Kokura S, Naito Y, Yoshikawa T. Recognition of endoscopic diagnosis in differentiated-type early gastric cancer by flexible spectral imaging color enhancement with indigo carmine. Digestion 86(2): 161-170, 2012.
73. Fukumoto K, Naito Y, Takagi T, Yamada S, Horie R, Inoue K, Harusato A, Hirata I, Omatsu T, Mizushima K, Hirai Y, Yoshida N, Uchiyama K, Ishikawa T, Handa O, Konishi H, Wakabayashi N, Yagi N, Kokura S, Ichikawa H, Kita M, Yoshikawa T. Role of tumor necrosis factor-a (TNF-a) in the pathogenesis of indomethacin-induced small intestinal injury in mice. Int J Mol Med 27(3): 353-359, 2011.
74. Yoshida N, Naito Y, Kugai M, Inoue K, Uchiyama K, Takagi T, Ishikawa T, Hand O, Konishi H, Wakabayashi N, Yagi N, Kokura S, Morimoto Y, Kanemasa K, Yanagisawa A, Yoshikawa T. Efficacy of hyaluronic acid in endoscopic mucosal resection of colorectal tumors. J Gastreonterol Hepatol 26(2): 286-291, 2011.
75. Yoshida N, Naito Y, Kugai M, Inoue K, Uchiyama K, Takagi T, Ishikawa T, Konishi H, Wakabayashi N, Kokura S, Yagi N, Morimoto Y, Yanagisawa A, Yoshikawa T. Efficacy of Magnifying Endoscopy with Flexible Spectral Imaging Color Enhancement in the Diagnosis of Colorectal Tumors. J Gastroenterol 46: 65-72, 2011.
76. Yamada S, Naito Y, Takagi T, Mizushima K, Horie R, Fukumoto K, Inoue K, Harusato A, Hirata I, Omatsu T, Yoshida N, Uchiyama K, Handa O, Ishikawa T, Konishi H, Wakabayashi N, Yagi N, Kokura　S, Kita M, Yoshikawa T. Reduced small-intestinal injury induced by indomethacin in interleukin-17A-deficient mice. J Gastroenterol Hepatol 26(2): 398-404, 2011.
77. Inoue K, Naito Y, Takagi T, Hayashi N, Hirai Y, Mizushima K, Horie R, Fukumoto K, Yamada S, Harusato A, Hirata I, Omatsu T, Yoshida M, Uchiyama K, Ishikawa T, Handa O, Konishi H, Wakabayashi N, Yagi N, Ichikawa H, Kokura S, Yoshikawa T.Daikenchuto, a Kampo medicine, regulates intestinal fibrosis by inhibiting heat shock protein 47 expression in a rat colitis model. Biol Pharm Bull 34: 1659-1665, 2011.
78. Kanbayashi Y, Hosokawa T, Okamoto K, Fujimoto S, Konishi H, Otsuji E, Yoshikawa T, Takagi T, Miki T, Taniwaki M Factors predicting requirement of high-dose transdermal fentanyl in opioid switching from oral morphine or oxycodone in patients with cancer pain. Clin J Pain 27(8): 664-667, 2011.
79. Soga K, Konishi H, Miyajima T, Yoshikawa T. Bleeding from major and minor duodenal papillae due to hemosuccus pancreaticus confirmed with side-view gastroduodenal endoscopy Indian J Gastroenterol 30(6):284, 2011.
80. Soga K, Sakagami J, Handa O, Konishi H, Wakabayashi N, Yagi N, Yamada M, Kokura S, Naito Y, Yoshikawa T, Arizono N. Long fish tapeworm in the intestine: an in situ observation by capsule endoscopyIntern Med 50(4): 325-327, 2011.
81. Kanbayashi Y, Hosokawa T, Okamoto K, Konishi H, Otsuji E, Yoshikawa T, Takagi T, Taniwaki M.Statistical identification of predictors fo peripheral neuropathy associated with administration of bortezomib, taxanes, oxaliplatin or vincristine using ordered logistic regression analysis. Anticancer Drugs 21(9): 877-881, 2010.
82. Fukumoto K, Konishi H, Soga K, Miyawaki K, Okano H, Minami M, Wakabayashi N, Mitsufuji S, Yoshida N, Takagi T, Yagi N, Naito Y, Kataoka K, Yoshikawa T. Successful endoscopic injection sclerotherapy of high-risk gastroesophageal varices in a cirrhotic patient with hemophilia A. Gastroenterol Res Pract 2010, 518260, 2010.
83. Yoshida N, Naito Y, Sakai K, Sumida Y, Kanemasa K, Inoue K, Morimoto Y, Konishi H, Wakabayashi N, Kokura S, Yagi N, Yanagisawa A, Yoshikawa T Outcome of endoscopic submucosal dissection for colorectal tumors in eldery people Int J Colorectal Dis 25(4): 455-461, 2010.
84. Yoshida N, Wakabayashi N, 　Kanemasa K, Sumida Y, Hasegawa D, Inoue K, Morimoto Y, Kashiwa A, Konishi H, Yagi N, Naito Y, Yanagisawa A, Yoshikawa T.Endoscopic submucosal dissection for colorectal tumors: technical difficulties and rate of perforation Endoscopy 41: 758-761, 2009.
85. Soga K, Tomikashi K, Miyawaki K, Fukumoto K, Wakabayashi N,, Konishi H, Mitsufuji S, Yoshida N, Kokura S, Naito Y, Kataoka K, Yoshikawa T. MELD score, Child-Pugh score, and decreased albumin as risk factors for gastric variceal bleeding Hepato-gastroenterology 56: 1552-1556, 2009.
86. Soga K, Tomikashi K, Miyawaki K, Okuda K, Sugiyama Y, Sekikawa S, Wakabayashi N, Konishi H, Mitsufuji S, Kataoka K, Yoshikawa T. Endoscopic injection sclerotherapy with ethanolamine oleate with iopamidol for esophagojejunal varices in idiopathic portal hypertension Dig Dis Sci 54: 1592-1596, 2009.
87. Soga K, Konishi H, Tatsumi N, Konishi C, Nakano K, Wakabayashi N, Mitsufuji S, Kataoka K, Okanoue T, Mukaisho K, Hattori T. Clear cell adenocarcinoma of the colon: A case report and review of literature. World J Gastroenteorol 14(7): 1137-1140, 2008.
88. Shiomi S, Toriie A, Imamura S, Konishi H, Mitsufuji S, Iwakura Y, Yamaoka Y, Ota H, Yamamoto T, Imanishi J, Kita M.IL-17 is involved in Helicobatcter pylori-induced gastric inflammatory responses in a mouse model Helicobacter 13: 518-524, 2008.
89. Morimoto Y, Nomura K, Tsutsumi Y, Ohshiro M, Fujimoto Y, Shimizu D, Wakabayashi N, Konishi H, Mitsufuji S, Matsumoto Y, Taniwaki M. Clostridium difficile-associated diarrhea with hematochezia is associated with ulcer formation Scand J Gastroenterol 43(8): 967-970, 2008.
90. Nakao H, Konishi H, Mitsufuji S, Yamauchi J, Yasu T, Taniguchi J, Wakabayashi N, Kataoka K, Okanoue T. Comparison of Clinical Features and Patient Background in Functional Dyspepsia and Peptic Ulcer. Digestive Diseases and Sciences, 52: 2152-2158, 2007.
91. Yoshida N, Nomura K, Wakabayashi N, Konishi H, Nishida K, Taki T, Mitsufuji S, Horiike S, Yanagisawa A, Yamagishi H, Nakamura S, Okanoue T, Taniwaki M. Cytogenetic and clinicopathological chracterization by fluorescence in situ hypridization on paraffin- embedded tissue and sections of twenty-six cases with malignant lymphoma of small intestine Scand J Gastroenterol 41: 212-2222, 2006.
92. Mitsufuji S, Nagoshi M, Tatsumi Y, Sakai M, Shiomi S, Wakabayashi N, Konishi H, Okano H, Kataoka K, Okanoue T. Argon plasma coagulation: IN VIVO tissue damage to the esophagus and stomach and clinical efficacy for early esophageal and gastric cancer Digestive Endoscopy 17: 21-27, 2005.
93. Nomura K, Kamitsuji Y, Kono E, Matsumoto Y, Yoshida N, Konishi H, Horiike S, Okanoue T, Taniwaki M. Severe cytomegalovirus enterocolitis after standard chemotherapy for non-Hodgkin’s lymphoma Scand J Gastroenterol 40: 604-606, 2005.
94. Nomura K, Fukumoto K, Shimizu D, Okuda T, Yoshida N, Kamitsuji Y, Matsumoto Y, Konishi H, Ueda Y, Horiike S, Okanoue T, Taniwaki M. Pseudomembranous colitis presenting as acute colonic obstruction without diarrhea in a patient with gastric Burkitt lymphoma World J Gastroenterol 11(7): 2681-2683, 2005.
95. Yamauchi J, Mitsufuji S, Taniguchi J, Sakai M, Tatsumi N, Yasuda Y, Konishi H, Wakabayashi N, Kataoka K, Okanoue T.Acute esophageal necrosis followed by upper endoscopy and esophageal manometry/pH test Dig Dis Sci 50(9): 1718-1721, 2005.
96. Tatsumi N, Mitsufuji S, Tatsumi Y, Wakabayashi N, Konishi H, Kataoka K, Okanoue T.Esophageal intramural pseudodiverticulosis: a case of a young woman Dig Dis Sci, 49(9):1556-1559, 2004.
97. Shimomura T, Ishiguro S, Konishi H, Wakabayashi N, Mitsufuji S, Kasugai T, Maenou M, Kodama T. New indication for endoscopic treatment of colorectal carcinoma with submucosal invasion. J Gastroenterol Hepatol 19: 48-55, 2004.
98. Yoshida N, Nomura K, Matsumoto Y, Nishida K, Wakabayashi N, Konishi H, Mitsufuji S, Kataoka K, Okanoue T, Taniwaki M. Detection of BCL2-IGH rearrangement on paraffin-embedded tissue sections obtained from a small submucosal tumor of the rectum in a patient with recurrent follicular lymphoma World J Gastroenterol 10(17): 2602- 2604, 2004.
99. Yoshida N, Wakabayashi N, 　Nomura K, Konishi H, Yamamoto H, Mitsufuji S, Kataoka K, Taniwaki M, Yamagishi H, Okanoue T. Ileal mucosa-associated lymphoid tissue lymphoma showing several ulcer scars detected using double-ballon endoscopy Endoscopy 36(11): 1022-1024, 2004.
100. Imamura S, Kita M, Yamaoka Y, Yamamoto T, Ishimaru A, Konishi H, Wakabayashi N, Mitsufuji S, Okanoue T, Imanishi J. Vector Potential of Cockroches for Helicobacter pylori Infection Am J Gastroenterol 98(7): 1500-1503, 2003.
101. Tatsumi Y, Konishi H, Nakajima T, Sakamoto Y, Yamane Y, Misawa S, Amaike H, Naito K. Endoscopic balloon dilation of postoperative duodenal stricture by using a new type of wire-guided balloon catheter. Digestive Endoscopy 13: 86-89, 2001.
102. Nakajima T, Konishi H, Sakamoto Y, Tatsumi Y, Itoh Y, Tokita K, Katoh M, Yamane Y, Okanoue T, Kashima K, Amaike H, Sugihara H, Tsuchihashi Y. Ischemic hepatitis induced by mesenteric volvulus in a patient with chronic obstructive lung disease. Journal of Gastroenterology, 35: 168-172, 2000.
103. Nakajima T, Konishi H, Tatsumi Y, Sakamoto Y, Yamane Y, Misawa S, Toyama S, Ochiai T, Kashima K, Konishi E, Tsuchihashi Y. Gastric cancer presenting with extremely rapid growth: unprecedented morphologic change in a short time and endoscopic estimation of its doubling time. Endoscopy 32: 994-997, 2000.
104. Kanemasa H，Ozawa H，Konishi H，Ito T，Nishi M，Mitsufuji S，Kodama T，Hattori T，Kawata M. Distribution of glucocorticoid receptor immunoreactivity in gastric mucosa of normal and adrenalectomized rats. Dig Dis Sci 44: 2081-2087, 1999.
105. Konishi H, Steinbach G, Terry NHA, Fujita K, Lee JJ, Ruifrok A, Spaulding D, Lynch PM, Dubin JA, Hattori T, Hittelman WN. S phase determination in intact colonic crypts by histone H3 mRNA in situ hybridization and confocal microscopy. Cancer Epidemiology, Biomarkers & Prevention 6: 531-536, 1997.
106. Konishi H, Steinbach G, Hittelman WN, Fujita K, Lee JJ, Glober GA, Levin B, Andreeff M, Goodacre AM, Terry NHA. Cell kinetic analysis of intact colonic crypts by confocal microscopy and immunofluorescence. Gastroenterology 111: 1499-1506, 1996.
107. Konishi H, Steinbach G, Terry NHA, Lee JJ, Dubin JA, Glober GA, Fujita K, Spaulding D, Cass L, Hittelman WN. Histone H3 messenger RNA in situ hybridization correlates with in vivo bromodeoxyuridine labeling of S-phase cells in rat colonic epithelium. Cancer Research 56: 434-437, 1996.
108. Yamaoka Y, Konishi H, Kodama T, Kashima K, Yamaguchi T, Imamura M, Ogasawara T, Kizu M. A case of gastric antral vascular ectasia-increase of neuroendocrine cells in the antrum. Journal of Gastroenterology, 30: 387-392, 1995.
109. Konishi H. Experimental gastric endocrine tumor in rodents. Journal of Kyoto Prefectural University of Medicine 104: 465-483, 1995.
110. Nakano K，Konishi H，Noda M，Sato H，Kodama T，Kashima K，Hattori T.　Regeneration of parietal cells at the healing process of acetic acidinduced gastric ulcers in rats-evaluation of the quality of ulcer healing by the administration of various agents　Acta Histochem Cytochem 28(1): 73-76, 1995.
111. Konishi H, Isetani K, Noda M, Kodama T, Kashima K. A case of metastatic chondrosarcoma of the stomach. Journal of Gastroenterology, 29: 495-500, 1994.