専　門

• 消化器病学
• 消化器内視鏡
• 消化器内視鏡治療

所属学会

• 日本消化器病学会専門医、近畿支部評議員
• 日本消化器内視鏡学会専門医
• 日本消化管学会胃腸科指導医
• 日本内科学会認定内科医

業　績

1. Kashiwagi S, Naito Y, Inoue R, Takagi T, Nakano T, Inada Y, Fukui A, Katada K, Mizushima K, Kamada K, Uchiyama K, Handa O, Ishikawa T, Itoh Y. Mucosa-Associated Microbiota in the Gastrointestinal Tract of Healthy Japanese Subjects. Digestion. 2019 Feb 5:1-14. doi: 10.1159/000496102.
2. Dohi O, Yagi N, Naito Y, Fukui A, Gen Y, Iwai N, Ueda T, Yoshida N, Kamada
   K, Uchiyama K, Takagi T, Konishi H, Yanagisawa A, Itoh Y. Blue laser imaging-bright improves the real-time detection rate of early gastric cancer: a randomized controlled study. Gastrointest Endosc. 2019 Jan;89(1):47-57. doi:10.1016/ j.gie.2018.08.049.
3. Handa O, Takayama S, Mukai R, Suyama Y, Majima A, Fukui A, Omatsu T, Naito Y. A review of the mechanism and prophylaxis of acetyl salicylic acid- induced injury of the small intestine. Free Radic Res. 2018 Dec;52(11-12):1266- 1270. doi: 10.1080/10715762.2018.1455003.
4. Suyama Y, Handa O, Naito Y, Takayama S, Mukai R, Ushiroda C, Majima A, Yasuda-Onozawa Y, Higashimura Y, Fukui A, Dohi O, Okayama T, Yoshida N, Katada K, Kamada K, Uchiyama K, Ishikawa T, Takagi T, Konishi H, Itoh Y. Mucus reduction promotes acetyl salicylic acid-induced small intestinal mucosal injury in rats. Biochem Biophys Res Commun. 2018 Mar 25;498(1):228-233. doi: 10.1016/j.bbrc.2018.02.202.
5. Yasuda-Onozawa Y, Handa O, Naito Y, Ushiroda C, Suyama Y, Toyokawa Y, Murakami T, Yasuda T, Ueda T, Majima A, Hotta Y, Doi T, Tanaka M, Horii Y, Higashimura Y, Mizushima K, Morita M, Uehara Y, Horie H, Fukui A, Dohi O, Okayama T, Yoshida N, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Konishi H, Itoh Y. Rebamipide upregulates mucin secretion of intestinal goblet cells via Akt phosphorylation. Mol Med Rep. 2017 Dec;16(6):8216-8222. doi: 10.3892/mmr.2017.7647.
6. Majima A, Handa O, Naito Y, Suyama Y, Onozawa Y, Higashimura Y, Mizushima K, Morita M, Uehara Y, Horie H, Iida T, Fukui A, Dohi O, Okayama T, Yoshida N, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Konishi H, Yasukawa Z, Tokunaga M, Okubo T, Itoh Y. Real-time monitoring of trans- epithelial electrical resistance in cultured intestinal epithelial cells: the barrier protection of water-soluble dietary fiber. J Dig Dis. 2017 Mar;18(3):151-159. doi: 10.1111/1751-2980.12456.
7. Fukui A, Naito Y, Handa O, Kugai M, Tsuji T, Yoriki H, Qin Y, Adachi S, Higashimura Y, Mizushima K, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Yagi N, Kokura S and Yoshikawa T. Acetyl salicylic acid induces damage to intestinal epithelial cells by oxidation-related modifications of ZO-1. Am J Physiol Gastrointest Liver Physiol. 2012. 303: G927–G936.